The observation of the foveal granular reflexes with multiple evanescent white dot syndrome.

PURPOSE: To evaluate the foveal granular reflexes (Jampol dots) in macula with multiple evanescent white dot syndrome (MEWDS) and describe the pathophysiology.

METHODS

Eighteen eyes of 18 MEWDS cases (4 male,14 female) were studied. We evaluated the presence and location of Jampol dots and classified them into micro and fused types based on the fundus appearance, and mixed type was included in the fused type. The findings of Jampol dots in optical coherence tomography (OCT) and en face OCT were investigated. A normal 18 eyes were also analyzed.

RESULTS

Jampol dots seen in (83%) 15 of 18 eyes: micro type in 5 eyes, fused type in 10 eyes. OCT showed more outer retinal damage in the fused type than in the micro type (10 of 10 eyes, 100% vs. 3 of 5 eyes, 60%). En face OCT showed two kinds of findings: hyperreflections in the superficial capillary slab and hyperreflections in the outer retinal slab. The mean visual acuity was worse in the fused type compared to the micro type.

CONCLUSIONS

Jampol dots with MEWDS were classified into two types, and their localization was found to be different. This could be useful in understanding the pathogenesis of MEWDS.