American ginseng improves ovarian dysfunction through miR-151-5p activation of BDNF/AKT/BCl-2/Bax signaling pathway in premature ovarian failure model rats: protein macromolecules and expression.

With the acceleration of the pace of modern life and the increase of environmental pressure, women are facing increasingly prominent health problems, ovarian dysfunction will not only lead to fertility decline, but also may lead to a series of endocrine disorders, seriously affecting women's quality of life. The purpose of this study was to explore the potential role of American panax panax in improving ovarian dysfunction by activating the BDNF/AKT/Bcl-2/Bax signaling pathway via miR-151-5p based on infrared thermal imaging technology. The study constructed an animal model of ovarian dysfunction, and used infrared thermal imaging technology to monitor the ovarian region in real time and record its temperature changes to evaluate the treatment effect. Through these data, we analyzed the activation effect of American ginseng extract on the signaling pathway and its relationship with the improvement of ovarian function. The results of the study showed that the infrared thermography of the ovarian region treated with American ginseng extract showed a significant increase in temperature, indicating increased ovarian blood flow and enhanced metabolic activity. These changes suggest that American ginseng extract can effectively activate the BDNF/AKT/Bcl-2/Bax signaling pathway, thereby improving ovarian dysfunction. The results showed that American ginseng extract can effectively promote the repair and functional recovery of ovarian tissue, and infrared thermal imaging technology has a good application prospect in monitoring the therapeutic effect.