Skin health and disease · 2026
Treatment outcomes using subcision combined with platelet-rich plasma for atrophic acne scars: a study in Vietnamese patients.
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Nguyen Lam Van, Lam Tan Tan
Аннотация
BACKROUND: Facial atrophic scars significantly impact self-confidence and quality of life. Recently, the combination of -platelet-rich plasma (PRP) and subcision has been proposed as a potential treatment modality; however, clinical trial results remain inconsistent.
OBJECTIVES: To assess the clinical efficacy and safety of combining subcision with PRP therapy for the treatment of facial atrophic acne scars in Vietnamese patients.
METHODS: A total of 44 patients with facial atrophic scars of grade 2 or higher were included in the study. Each patient underwent three treatment sessions using a combination of subcision and PRP at 4-week intervals. The patients were evaluated by three independent reviewers through a series of sequential photographs taken 1 month after the third treatment session.
RESULTS: All patients presented with atrophic scars on the cheeks, predominantly mixed scars caused by acne (96%). At evaluation timepoints, the Goodman and Baron grading scale demonstrated significant improvement, with statistically significant differences (P < 0.05). Following the treatment regimen of subcision combined with PRP, the majority of patients achieved good-to-excellent responses (96%) and reported satisfaction with the treatment outcomes (96%). Common side effects included pain (93%), mild swelling (41%) and erythema (34%), all of which were transient. The baseline severity of scars (Goodman and Baron) and the presence of rolling scars significantly influenced treatment efficacy (P < 0.05).
CONCLUSIONS: The combination of subcision and PRP is an effective and safe approach for the treatment of atrophic scars, providing significant improvement and high patient satisfaction.
OBJECTIVES: To assess the clinical efficacy and safety of combining subcision with PRP therapy for the treatment of facial atrophic acne scars in Vietnamese patients.
METHODS: A total of 44 patients with facial atrophic scars of grade 2 or higher were included in the study. Each patient underwent three treatment sessions using a combination of subcision and PRP at 4-week intervals. The patients were evaluated by three independent reviewers through a series of sequential photographs taken 1 month after the third treatment session.
RESULTS: All patients presented with atrophic scars on the cheeks, predominantly mixed scars caused by acne (96%). At evaluation timepoints, the Goodman and Baron grading scale demonstrated significant improvement, with statistically significant differences (P < 0.05). Following the treatment regimen of subcision combined with PRP, the majority of patients achieved good-to-excellent responses (96%) and reported satisfaction with the treatment outcomes (96%). Common side effects included pain (93%), mild swelling (41%) and erythema (34%), all of which were transient. The baseline severity of scars (Goodman and Baron) and the presence of rolling scars significantly influenced treatment efficacy (P < 0.05).
CONCLUSIONS: The combination of subcision and PRP is an effective and safe approach for the treatment of atrophic scars, providing significant improvement and high patient satisfaction.