Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2007
[Therapeutic result of operation combined with large-dose of roferon-A for cutaneous malignant melanoma].
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Wang Yaojun, Cen Ying, Li Zhengyong
Аннотация
OBJECTIVE: To observe the effects of operation with large-dose of Roferon-A for cutaneous malignant melanoma.
METHODS: From January 1998 to December 2005, thirty-three patients with cutaneous malignant melanoma were treated. There were 20 males and 13 females, aging 17-79 years. The disease course was 2 months to 7 years. In 33 patients, nine patients identified as clinical-stage I received singly enlarged-resection to the primary lesion and performed split-thickness skin graft dermoplasty or adjacent skin flap repair; twenty-three patients identified as clinical-stage II received enlarged-resection to the primary lesion and performed proximal lymphaden scavenge as well as received split-thickness skin graft dermoplasty; and one patient identified as clinical-stage III received palliative resection to the primary lesion. All patients received large dose of, Roferon-A after operation.
RESULTS: There are no recidivation in the 9 patients of clinical-stage I. There are 1 recidivation and 1 quit in all the 23 patients of clinical-stage II. One patient of clinical-stage III died after 18 months of operation.
CONCLUSION: The operation combined with large-dose of Roferon-A after operation was a more effective way to treat cutaneous malignant melanoma.
METHODS: From January 1998 to December 2005, thirty-three patients with cutaneous malignant melanoma were treated. There were 20 males and 13 females, aging 17-79 years. The disease course was 2 months to 7 years. In 33 patients, nine patients identified as clinical-stage I received singly enlarged-resection to the primary lesion and performed split-thickness skin graft dermoplasty or adjacent skin flap repair; twenty-three patients identified as clinical-stage II received enlarged-resection to the primary lesion and performed proximal lymphaden scavenge as well as received split-thickness skin graft dermoplasty; and one patient identified as clinical-stage III received palliative resection to the primary lesion. All patients received large dose of, Roferon-A after operation.
RESULTS: There are no recidivation in the 9 patients of clinical-stage I. There are 1 recidivation and 1 quit in all the 23 patients of clinical-stage II. One patient of clinical-stage III died after 18 months of operation.
CONCLUSION: The operation combined with large-dose of Roferon-A after operation was a more effective way to treat cutaneous malignant melanoma.