American journal of obstetrics and gynecology · 2002
The effect of ketorolac on postoperative febrile episodes in patients after abdominal myomectomy.
Клиническое исследованиеСравнительное исследованиеСтатьяРандомизированное исследованиеПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Held Barbara I, Michels Anne, Blanco Jody, Ascher-Walsh Charles
Аннотация
OBJECTIVE: Our purpose was to determine whether administering the anti-inflammatory agent ketorolac after abdominal myomectomy reduces the incidence of febrile episodes.
STUDY DESIGN: This prospective, randomized, double-blinded, placebo-controlled clinical investigation compared administering ketorolac 15 mg intravenously every 6 hours beginning in the recovery room with saline solution administered in the same regimen in 122 patients undergoing abdominal myomectomy in a large, urban academic medical center. The primary outcome was fever >101.0 degrees F in the postoperative period. Results were analyzed by chi(2) analysis, independent samples t test, and logistic regression.
RESULTS: Data were analyzed on 112 patients, with 56 in the treatment group and 56 in the placebo group. After confounding factors were controlled with logistic regression, the data revealed a statistically significant reduction in febrile episodes in the ketorolac-treated group (27%) compared with the saline solution-treated group (41%) (P =.04).
CONCLUSION: Treatment with ketorolac after abdominal myomectomy results in a statistically significant reduction in the rate of febrile episodes.
STUDY DESIGN: This prospective, randomized, double-blinded, placebo-controlled clinical investigation compared administering ketorolac 15 mg intravenously every 6 hours beginning in the recovery room with saline solution administered in the same regimen in 122 patients undergoing abdominal myomectomy in a large, urban academic medical center. The primary outcome was fever >101.0 degrees F in the postoperative period. Results were analyzed by chi(2) analysis, independent samples t test, and logistic regression.
RESULTS: Data were analyzed on 112 patients, with 56 in the treatment group and 56 in the placebo group. After confounding factors were controlled with logistic regression, the data revealed a statistically significant reduction in febrile episodes in the ketorolac-treated group (27%) compared with the saline solution-treated group (41%) (P =.04).
CONCLUSION: Treatment with ketorolac after abdominal myomectomy results in a statistically significant reduction in the rate of febrile episodes.