Clinical imaging · 2016
Malignant pleural mesothelioma: initial experience in integrated (18)F-FDG PET/MR imaging.
Сравнительное исследованиеСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Schaarschmidt Benedikt M, Sawicki Lino M, Gomez Benedikt, Grueneisen Johannes, Hoiczyk Mathias, Heusch Philipp, Buchbender Christian
Аннотация
PURPOSE: This study aims to compare staging results of (18)F-FDG PET/computed tomography (CT) and integrated PET/magnetic resonance (MR) in malignant pleural mesothelioma (MPM) patients and to investigate a potential apparent diffusion coefficient (ADC)/SUV correlation.
MATERIALS AND METHODS: Six patients with MPM underwent (18)F-FDG PET/CT and PET/MR including diffusion-weighted imaging. Thoracic TNM staging was performed for both modalities. SUV and ADC were assessed in therapy-naive pleural lesions.
RESULTS: In thoracic TNM staging, no differences were found between PET/CT and PET/MR. An inverse correlation was observed between SUVmean and ADCmin (r=-0.63, P=.002).
CONCLUSION: MPM can be staged using PET/MR. The inverse correlation ADC/SUV indicates that future research on multiparametric therapy response evaluation may be warranted.
MATERIALS AND METHODS: Six patients with MPM underwent (18)F-FDG PET/CT and PET/MR including diffusion-weighted imaging. Thoracic TNM staging was performed for both modalities. SUV and ADC were assessed in therapy-naive pleural lesions.
RESULTS: In thoracic TNM staging, no differences were found between PET/CT and PET/MR. An inverse correlation was observed between SUVmean and ADCmin (r=-0.63, P=.002).
CONCLUSION: MPM can be staged using PET/MR. The inverse correlation ADC/SUV indicates that future research on multiparametric therapy response evaluation may be warranted.