Primary Non-Hodgkin's Lymphomas of the Nasal and Mouth Cavity and the Waldeyer's Ring: A morphological and immunohistochemical study.

Twenty-six non-Hodgkin's malignant lymphomas (ML) of the Waldeyer's ring, the mouth and nasal cavities were studied morphologically and immunohistochemically on paraffin and frozen sections. A B-cell origin was shown in all 14 cases of Waldeyer's ring M.L., while 5 of 7 nasal and 3 of 5 buccal cases were of T-cell nature. Seventy-nine per cent of all the above ML were high-grade malignancies. Combined morphological and immunohistochemical studies of such malignant lymphomas in Western populations have been reported rarely and are rather limited. The documentation of the first nasal and buccal cases of anaplastic Ki-1 positive peripheral T-cell ML is emphasised in conjunction with the more frequent carcinomas of the same anatomical areas under consideration.