Obstetrics and gynecology · 2011
Urine screening for Chlamydia trachomatis during pregnancy.
Сравнительное исследованиеСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Roberts Scott W, Sheffield Jeanne S, McIntire Don D, Alexander James M
Аннотация
OBJECTIVE: To compare the rates of Chlamydia trachomatis detection using urine and cervical secretions from pregnant women at our institution.
METHODS: A large cross-sectional sample of pregnant women (N=2,018) at 35-37 weeks of gestation were tested for C trachomatis with both endocervical and urine sampling using the Aptima Combo 2 Assay.
RESULTS: A prevalence of 4.3% and 4.1% were found for Chlamydia endocervical and urine samples, respectively. There was no difference between the two tests by McNemar's test (-0.02%, 0.32%; P=.083). There was excellent correlation between the tests found by the κ statistic (0.982 [0.961-1.000]).
CONCLUSION: Urine sampling for C trachomatis is equivalent to endocervical sampling in pregnancy using the Aptima 2 Combo Assay.
LEVEL OF EVIDENCE: II.
METHODS: A large cross-sectional sample of pregnant women (N=2,018) at 35-37 weeks of gestation were tested for C trachomatis with both endocervical and urine sampling using the Aptima Combo 2 Assay.
RESULTS: A prevalence of 4.3% and 4.1% were found for Chlamydia endocervical and urine samples, respectively. There was no difference between the two tests by McNemar's test (-0.02%, 0.32%; P=.083). There was excellent correlation between the tests found by the κ statistic (0.982 [0.961-1.000]).
CONCLUSION: Urine sampling for C trachomatis is equivalent to endocervical sampling in pregnancy using the Aptima 2 Combo Assay.
LEVEL OF EVIDENCE: II.