Human amniotic membrane graft with viscodissection and intraoperative OCT for macular hole repair.

OBJECTIVE

To present the human amniotic membrane (hAM) graft with the novel addition of viscodissection and usage of intraoperative OCT as a potential approach to treating challenging macular holes and to describe the outcomes.

DESIGN

Retrospective interventional case series.

PARTICIPANTS

10 patients with large, chronic, or persistent macular holes were included in this study.

METHODS

10 eyes of 10 patients were treated using a hAM graft with viscodissection. Intraoperative OCT was utilized to assist the placement of the graft. Outcomes were monitored through clinical examinations, retinal imaging, and OCT.

RESULTS

Macular holes were closed in all 10 patients and remained so during the entirety of the follow-up periods. 9 out of 10 patients experienced an improvement in visual acuity. Mean best corrected visual acuity increased from 1.68 logMAR (20/1000) preoperative to 0.74 logMAR (20/100) at 6 months postoperative. No adverse events were observed for any of our patients.

CONCLUSIONS

The addition of viscodissection to the standard hAM graft surgery is a potential optimization that reduces risks of iatrogenic damage to the retina. Surgeons can consider including this approach as part of their arsenal to treat such macular holes.