Empty sella syndrome in thyroid cancer survivor.

Empty sella syndrome is a consequence of the herniation of the subarachnoid space within the sella associated with flattering of the pituitary gland. In this paper, we describe the atypical clinical manifestation of this condition in a 27-year-old survivor of thyroid cancer. We associate the development of empty sella syndrome in this subject with normalization of levothyroxine treatment in conditions of long-lasting and inaccurately managed thyroid ablation-induced hypothyroidism. Administration of hydrocortisone and implementation of hypogonadism treatment together with the appropriate management of hypothyroidism led to a significant improvement in the patient's condition.