[Formation of NO and H2O2 in endometrial stromal cells under the effect of acetylcholine].

While conducting the experimental work the possibility both the basal and activated by acetylcholine NO and H2O2 production by uterus endometrium stromal cells was estimated. The results obtained give a ground to suppose the existence of two types of cholinoreceptors in the tesyed cells via which two signal transduction ways are fulfilled. The concentrational and temporal dependancy of these metabolites synthesis have a cyclic character. The hypothesis is revealed about a principal possibility of NO and N2O2 to come forward in the role of secondary messengers of the endometrium stromal cells as well as prrovide for the paracrine regulation of myometrium functioning.