What is the future of 'organ transplantation' in the head and neck?

PURPOSE OF REVIEW: To update readers on the current state and future of head and neck tissue transplantation.

RECENT FINDINGS: Many exciting advances have recently occurred in the field of head and neck transplantation and regenerative medicine. Larynx, face, and trachea transplants have all been successfully performed. Significant advancements in tissue engineering have occurred, including the ability to generate three-dimensional tissue structures. Transplantation of regenerated tissues has been successfully incorporated into airway reconstruction.

SUMMARY: These exciting advancements set the foundation to expand reconstructive options for dysfunctional tissues and to improve a patient's quality of life.