DEN open · 2023
Local recurrence of submucosal invasive colorectal cancer after endoscopic submucosal dissection revealed by copy number variation.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Okazawa Yu, Sugimoto Kiichi, Ii Yuki, Irie Takahiro, Kawaguchi Megumi, Kobari Aya, Momose Hirotaka, Tsuchiya Yuki, Amemiya Kota, Motegi Shunsuke, Tsukamoto Ryoichi, Kure Kazumasa, Honjo Kumpei, Ro Hisashi, Takahashi Rina, Kawano Shingo, Kawai Masaya, Ishiyama Shun, Takahashi Makoto, Kojima Yutaka, Tomiki Yuichi, Arakawa Atsushi, Yao Takashi, Satomi Kaishi, Matsushita Yuko, Ichimura Koichi, Sakamoto Kazuhiro
Аннотация
We report a case in which analysis of copy number variation revealed local recurrence of submucosal invasive colorectal cancer after curative endoscopic submucosal dissection (ESD). An 86-year-old man with a history of abdominoperineal resection of the rectum for rectal cancer underwent resection with ESD for early-stage sigmoid cancer 5 cm away from the stoma opening. At the same time, ileocecal resection was performed for advanced cecal cancer. Twelve months after ESD, advanced cancer occurred in the area of the ESD lesion. It was unclear if the cancer was a local recurrence after ESD, implantation of cecal cancer, or a new lesion. Copy number variation analysis performed for the three lesions revealed that the new lesion originated from residual tumor cells from ESD and was unlikely to be cecal cancer.