Journal of pharmacy & bioallied sciences · 2025
An Observational Study to Correlate Severity of Lower Urinary Tract Symptoms and Size of Median Lobe of Prostate by Digital Rectal Examination in Patients with Benign Prostate Hyperplasia.
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Dubey Ashish K, Asati Aashutosh, Chourasia Mayank, Vithani Hemal, Saad Talha, Tirkey Abhay S, Kunkal Uppal R
Аннотация
BACKGROUND: This observational study evaluated the correlation between median lobe size assessed by digital rectal examination (DRE) and the severity of lower urinary tract symptoms (LUTS) in benign prostatic hyperplasia (BPH) patients.
METHODS: A total of 120 men aged ≥50 years were assessed using the International Prostate Symptom Score (IPSS) and DRE for median lobe grading. Correlations were analyzed using Spearman's coefficient and ANOVA.
RESULTS: Larger median lobe size significantly correlated with higher LUTS severity (P < 0.001), with mean IPSS scores of 7.6 (small), 15.4 (moderate), and 24.1 (large lobes).
CONCLUSION: Median lobe enlargement is associated with severe LUTS in BPH, highlighting the importance of thorough clinical prostate evaluation.
METHODS: A total of 120 men aged ≥50 years were assessed using the International Prostate Symptom Score (IPSS) and DRE for median lobe grading. Correlations were analyzed using Spearman's coefficient and ANOVA.
RESULTS: Larger median lobe size significantly correlated with higher LUTS severity (P < 0.001), with mean IPSS scores of 7.6 (small), 15.4 (moderate), and 24.1 (large lobes).
CONCLUSION: Median lobe enlargement is associated with severe LUTS in BPH, highlighting the importance of thorough clinical prostate evaluation.