Медицинская библиотека · Zhonghua nan ke xue = National journal of andrology · 2003

[Effect of immunological orchitis on sperm specific enzyme and fertility].

Chen Lei, Xia Wei-Ping, Zhou Zhi-Heng

Аннотация на английскомСтатьяПеревод пока не подготовлен

Аннотация

OBJECTIVE

To investigate the effect of immunological orchitis on spermatic specific enzyme and fertility.

METHODS

Experimental allergic orchitis (EAO) model of guinea pigs was duplicated. The histological and morphological changes of spermatic acrosomal protease and hyaluronidase, lactate dehydrogenase, sperm in epididymis and testes were observed by means of enzyme kinetical spectrophotometry and gelatin fixation of substrate thin membrane.

RESULTS

The activity of acrosomal protease, hyaluronidase and spermatic cytoplasmic lactic dehydrogenase in the epididymis acrosomal enzyme system became low, and so did the quality of sperm in epididymis. Remarkable morphological changes of spermatogenic cells developed in the convoluted seminiferous tubules.

CONCLUSIONS

EAO remarkably affects the fertility of male guinea pigs. The orchis and epididymal sperms might be the sites of action.

Для цитирования: Chen Lei, Xia Wei-Ping, Zhou Zhi-Heng. [Effect of immunological orchitis on sperm specific enzyme and fertility].. Zhonghua nan ke xue = National journal of andrology. 2003.

Предметные рубрики MeSH

Acrosin Animals Autoimmune Diseases Disease Models, Animal Fertility Guinea Pigs L-Lactate Dehydrogenase Male Orchitis Spermatozoa Testis

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