[Adrenergic mechanisms in the formation of adaptive response of different tissues].

The proliferative tissue activity of the small intestine, kidney, liver and submandibular salivary gland was studied in 10-h immobilization after blocking peripheral beta-adrenoreceptors by obsidan. It is shown that the proliferation increased in all the tissues examined, except the submandibular gland. The injection of obsidan before and during immobilization led to a decrease and delay of DNA synthesis (the intestine, liver), short-term proliferative inhibition (kidney), to stimulation of stress-inhibited proliferation (submandibular gland). It is suggested that the pattern of tissue adaptive response is defined by beta-adrenergic mechanisms.