[CAUSES OF DEVELOPMENT AND CLINICAL COURSE OF RESPIRATORY TUBERCULOSIS IN ADOLESCENTS WITH AGENT DRUG RESISTANT].

The aim of the study was to study the clinical manifestations and causes of the development of drug-resistant tuberculosis in adolescents. Clinical manifestations and causes of tuberculosis development were analyzed in 138 adolescents who were under care in the Aktyubinsk Regional TB Dispensary for the period 2005 - 2016. The main reasons for the development of drug-resistant tuberculosis was the presence of close contact with the patient who discharges mycobacterium tuberculosis, resistant to anti-tuberculosis drugs, lives in socially deprived families and has residual changes in the lungs. The spectrum coincidence of drug resistance with the source of tuberculosis infection was 76.2%. The marked clinical manifestations, the presence of lung tissue destruction, bacterial excretion, a high percentage of complications and damage of the bronchi are specific for drug-resistant respiratory tuberculosis.