Abdominal imaging · 2002
Measurement of the apparent diffusion coefficient in intraductal mucin-producing tumor of the pancreas by diffusion-weighted echo-planar MR imaging.
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Irie H, Honda H, Kuroiwa T, Yoshimitsu K, Aibe H, Shinozaki K, Masuda K
Аннотация
BACKGROUND: We investigated whether diffusion-weighted echo-planar magnetic resonance (MR) imaging can help differentiate intraductal mucin-producing tumors of the pancreas from other cystic lesions.
METHODS: Diffusion-weighted echo-planar MR imaging was performed in patients with mucin-producing tumors (n = 19), pseudocysts (n = 9), chronic pancreatitis with diffuse main pancreatic dilatation (n = 5), and serous cystadenomas (n = 2). Images were obtained with diffusion sensitizing gradients of 30, 300, and 900 s/mm2. The apparent diffusion coefficient (ADC) was calculated.
RESULTS: The mean (+/- standard deviation) ADCs of mucin-producing tumors (2.8 x 10(-3) mm2/s +/- 1.0 x 10(-3)), pseudocysts (2.9 x 10(-3) mm2/s +/- 1.2 x 10(-3)), dilated main pancreatic duct in chronic pancreatitis (3.3 x 10(-3) mm2/s +/- 1.2 x 10(-3)), serous cystadenomas (2.9 x 10(-3) and 2.6 x 10(-3) mm2/s), and cerebrospinal fluid (3.5 x 10A(-3) mm2/s +/- 1.1 x 10(-3)) were not statistically different.
CONCLUSION: It is difficult to differentiate between mucin-producing tumors and other cystic lesions by ADC measurements when using diffusion-weighted echo-planar MR imaging.
METHODS: Diffusion-weighted echo-planar MR imaging was performed in patients with mucin-producing tumors (n = 19), pseudocysts (n = 9), chronic pancreatitis with diffuse main pancreatic dilatation (n = 5), and serous cystadenomas (n = 2). Images were obtained with diffusion sensitizing gradients of 30, 300, and 900 s/mm2. The apparent diffusion coefficient (ADC) was calculated.
RESULTS: The mean (+/- standard deviation) ADCs of mucin-producing tumors (2.8 x 10(-3) mm2/s +/- 1.0 x 10(-3)), pseudocysts (2.9 x 10(-3) mm2/s +/- 1.2 x 10(-3)), dilated main pancreatic duct in chronic pancreatitis (3.3 x 10(-3) mm2/s +/- 1.2 x 10(-3)), serous cystadenomas (2.9 x 10(-3) and 2.6 x 10(-3) mm2/s), and cerebrospinal fluid (3.5 x 10A(-3) mm2/s +/- 1.1 x 10(-3)) were not statistically different.
CONCLUSION: It is difficult to differentiate between mucin-producing tumors and other cystic lesions by ADC measurements when using diffusion-weighted echo-planar MR imaging.