JBJS case connector · 2026
Diagnostic Challenges in Oncogenic Osteomalacia due to Intracranial Phosphaturic Mesenchymal Tumor: A Case Report.
СтатьяКлинический случайНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Ошибки и ограничения
История · было → стало
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Sivakumar Singanallur Palanivelayutham, Senthil Kannan Venkatesan, Duvuru Shyam, Irfan Mahshook, Dheenadhayalan Jayaramaraju, Rajasekaran Shanmuganathan
Аннотация
CASE: A 37-year-old man presented with multiple fragility fractures and profound weakness. Evaluation revealed hypophosphatemia and an elevated serum fibroblast growth factor-23. A Ga-68 DOTANOC PET-CT localized a phosphaturic mesenchymal tumor in the sphenoid bone. Surgical resection was performed with immunohistochemistry confirming the diagnosis and leading to rapid biochemical normalization. The patient showed progressive fracture healing and made a complete functional recovery by 12 months.
CONCLUSION: Intracranial phosphaturic mesenchymal tumors are a rare cause of tumor-induced osteomalacia. This case underscores that in patients with unexplained fractures, systematic serum phosphate testing is critical. Functional imaging is essential for tumor localization, and complete surgical excision is curative.
CONCLUSION: Intracranial phosphaturic mesenchymal tumors are a rare cause of tumor-induced osteomalacia. This case underscores that in patients with unexplained fractures, systematic serum phosphate testing is critical. Functional imaging is essential for tumor localization, and complete surgical excision is curative.