[Clinical analysis of 15 patients with primary malignant melanoma in the genital tract].

OBJECTIVE

To analyse the clinical characteristics and prognosis of primary malignant melanoma in female genital tract.

METHODS

Clinical data of 15 patients with primary malignant genital melanoma were analysed retrospectively. The tumors occurred in the vulva (4 patients), in vagina (9) and in uterine cervix (2). 11 of them were treated by surgery combined with chemotherapy and immunotherapy, the remaining 4 by chemotherapy and immunotherapy only.

RESULTS

All cases except one were followed up. The survival periods were shorter than 1 year in 5 patients, shorter than 2 years in 7. Two were alive for more than 3 years and 1 for more than 19 years.

CONCLUSIONS

The prognosis of primary malignant melanoma is rather poor. Surgery combined of chemotherapy and immunotherapy is the main therapeutic approach.