Clofarabine-induced acral erythema during the treatment of patients with myelodysplasia and acute leukemia: report of two cases.

Acral erythema has been associated with a number of chemotherapeutic agents, but there are no reports of clofarabine-induced acral erythema in the literature. We describe two patients who developed acral erythema after receiving clofarabine. One patient had myelodysplastic syndrome while the other had acute lymphoblastic leukemia.