Exogenous melatonin: morphology and kallikrein activity of male Syrian hamster submandibular gland.

Seven weeks of daily melatonin administration resulted in substantial reduction of convoluted duct cell granule population and kallikrein activity. Some reduction of intercalated duct cell granules was also observed. Testes weight and size was also dramatically reduced. All these changes were not observed after three weeks of melatonin injection.