Liporeinjection of Fat, Nanofat, and Stromal Vascular Fraction.

Autologous fat transfer has progressed from a volumetric filler to a regenerative cornerstone in modern facial plastic and reconstructive surgery. This article reviews the biological basis, technical refinements, and current processing systems that underpin facial fat grafting. Adipose tissue functions as both a biocompatible filler and a regenerative organ enriched with adipose-derived stem cells and stromal vascular fraction, driving angiogenesis, collagen remodeling, and skin rejuvenation. Commercial systems Puregraft, REVOLVE, Lipocube, and Tulip Nanofat are compared in terms of purification mechanisms, benefits, and clinical use. These closed sterile systems enhance safety, standardization, and predictability, bridging aesthetic artistry with regenerative science.