Journal of cutaneous pathology · 2002
Primary cutaneous lymphoblastic lymphoma presenting in an 8-week old infant.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Trupiano Jacqueline K, Bringelsen Karen, Hsi Eric D
Аннотация
BACKGROUND: We report a case of primary cutaneous lymphoblastic lymphoma (LBL) presenting in an 8-week-old infant.
METHODS: Histopathology and flow cytometric analysis confirmed the diagnosis of a lymphoblastic lymphoma. The cells expressed CD19, CD20, CD34 and surface immunoglobulin (sIg).
RESULTS: The cells were negative for TdT and CD99. This unusual immunophenotype has been described as "transitional pre-B-cell", in that the cells express both immature markers (CD34) and mature markers (sIg).
CONCLUSIONS: To our knowledge, only five other cases of sIg positive precursor B-cell LBL have been reported in the literature. This may represent the youngest reported case of primary cutaneous LBL, occurring at 8weeks of age.
METHODS: Histopathology and flow cytometric analysis confirmed the diagnosis of a lymphoblastic lymphoma. The cells expressed CD19, CD20, CD34 and surface immunoglobulin (sIg).
RESULTS: The cells were negative for TdT and CD99. This unusual immunophenotype has been described as "transitional pre-B-cell", in that the cells express both immature markers (CD34) and mature markers (sIg).
CONCLUSIONS: To our knowledge, only five other cases of sIg positive precursor B-cell LBL have been reported in the literature. This may represent the youngest reported case of primary cutaneous LBL, occurring at 8weeks of age.