The American journal of gastroenterology · 1996
Variant of intraductal carcinoma (with scant mucin production) is of main pancreatic duct origin: a clinicopathological study of four patients.
Сравнительное исследованиеСтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Suda K, Hirai S, Matsumoto Y, Mogaki M, Oyama T, Mitsui T, Fujibayashi M, Kumazawa K, Kajiwara T
Аннотация
OBJECTIVES: To investigate the histopathological and immunohistochemical features of intraductal "nodular" tumor located in the main pancreatic duct.
METHODS: Four cases were studied, and the results were compared with those in 10 cases of common ductal adenocarcinomas of the pancreas.
RESULTS: The intraductal nodular carcinoma were large, more than 3 cm in diameter (range, 3-7 cm), lacked macroscopic mucin production, and presented a papillotubular adenocarcinoma. These tumors showed minimal invasion into the periductal tissue, duodenum, and choledochus. Immunohistochemically, the tumor cells were negative for anti-CEA and faintly positive for anti-CA19-9, in all except one tumor, whereas the common ductal adenocarcinomas were clearly positive for both. The postoperative course was favorable, and all three living patients remained healthy for more than 4 yr.
CONCLUSION: These tumors may be variants of intraductal tumors with a more favorable prognosis.
METHODS: Four cases were studied, and the results were compared with those in 10 cases of common ductal adenocarcinomas of the pancreas.
RESULTS: The intraductal nodular carcinoma were large, more than 3 cm in diameter (range, 3-7 cm), lacked macroscopic mucin production, and presented a papillotubular adenocarcinoma. These tumors showed minimal invasion into the periductal tissue, duodenum, and choledochus. Immunohistochemically, the tumor cells were negative for anti-CEA and faintly positive for anti-CA19-9, in all except one tumor, whereas the common ductal adenocarcinomas were clearly positive for both. The postoperative course was favorable, and all three living patients remained healthy for more than 4 yr.
CONCLUSION: These tumors may be variants of intraductal tumors with a more favorable prognosis.