Total Hip Arthroplasty, via Direct Anterior Approach, With Contralateral Proximal Femur Amputation.

Lower limb amputation has been well characterized in the literature to cause resultant osteoarthritis in the hip of the contralateral limb. This further amplifies the already significant physical disability and morbidity that come with lower limb amputation. The use of total hip arthroplasty (THA) in patients with lower limb amputations is rare, with available literature subsequently also limited. In this case report, we describe a 52-year-old female with a right proximal femur (subtrochanteric) amputation who underwent left THA due to osteoarthritis. To our knowledge, this is the first published report describing THA, via direct anterior approach, in a patient with contralateral proximal femur (subtrochanteric) amputation. We discuss the complex surgical considerations for this patient population, selection of approach, prosthesis, and postoperative outcomes.