The clinical, serological, pathological and immunocytochemical features of a case of primary carcinoma of the fallopian tube.

We report the case of a patient with Stage I fallopian tube carcinoma who underwent bilateral salpingo-oophorectomy, total hysterectomy, omentectomy and appendicectomy followed by cisplatin based chemotherapy. CA 125 antigen was immunocytochemically detected in more than 50% of neoplastic cells, and serum CA 125 assay correlated with the clinical course of disease. Since CA 125 levels progressively increased during chemotherapy, an immunoscintigraphy with 111 In labeled CA 125 monoclonal antibody was performed and revealed a 5 cm area of abnormal captation placed in the posterior abdominal wall next the left kidney. A CAT scan detected an enlargement of left para-aortic lymph nodes, without cleavage plane with the left psoas muscle. The present case confirms that serum CA 125 assay is a useful noninvasive tool in the management of fallopian tube carcinoma.