Journal of pharmacy & bioallied sciences · 2024
Assessing the Role of Clinicopathologic Factors in Outcome Prediction in Subjects Having Oropharyngeal Carcinoma Associated with Human Papillomavirus and Managed with Surgery.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Kumar Harsh, Sandhu Rameet, Upadhyay Ritesh, Aggarwal Aanchal, Rela Rathi, Karthik Sahana
Аннотация
BACKGROUND: Human papillomavirus (HPV) has been linked as a potential risk factor for increasing incidence of oropharyngeal carcinoma.
AIM: The present study aimed to evaluate the role of clinicopathologic factors in outcome prediction in subjects having oropharyngeal carcinoma associated with HPV and managed with surgery.
METHODS: The present retrospective study assessed data from 54 subjects that were diagnosed with stage III or IV HPV-associated oropharyngeal carcinoma were managed with surgery with or without adjuvant therapy.
RESULTS: The mean follow-up duration in the study subjects was 2.7 years. The recurrence-free survival and overall survival rates [age, number of lymph nodes involved, stage of tumor, and Charleston comorbidity index] in the study subjects were 83% and 71% and 62% and 79%, respectively. The recurrence rate in the study was found to be 21%.
CONCLUSION: The conclusion drawn from the present study is that some associated potential risk factors can have lesser relevance in HPV-associated oropharyngeal carcinoma.
AIM: The present study aimed to evaluate the role of clinicopathologic factors in outcome prediction in subjects having oropharyngeal carcinoma associated with HPV and managed with surgery.
METHODS: The present retrospective study assessed data from 54 subjects that were diagnosed with stage III or IV HPV-associated oropharyngeal carcinoma were managed with surgery with or without adjuvant therapy.
RESULTS: The mean follow-up duration in the study subjects was 2.7 years. The recurrence-free survival and overall survival rates [age, number of lymph nodes involved, stage of tumor, and Charleston comorbidity index] in the study subjects were 83% and 71% and 62% and 79%, respectively. The recurrence rate in the study was found to be 21%.
CONCLUSION: The conclusion drawn from the present study is that some associated potential risk factors can have lesser relevance in HPV-associated oropharyngeal carcinoma.