Parietal and frontal contributions to episodic encoding of location.

Specific contributions of frontal and parietal regions to visuospatial encoding and attention remain controversial. This study used fMRI to examine associative encoding of sequentially-presented spatial cues and object stimuli. The cue preceded the centrally-displayed object by a jittered-delay-interval to better isolate attempt and success in episodically integrating pure location information with separately presented objects. Superior parietal response was modulated by attempted location binding, while superior/middle frontal response was predictive of successful location binding.