Optical Coherence Tomography with Gapped Spectrum Using Sparse Iterative Covariance-Based Estimation.

Optical coherence tomography (OCT) is an optical imaging modality that provides high-resolution cross-sectional imaging of biological tissues noninvasively. In Fourier-domain OCT, axial resolution is governed by both the center wavelength and the spectral bandwidth of the light source; therefore, limited or discontinuous bandwidth degrades depth resolution and introduces sidelobes and artifacts in OCT images. To address these issues in OCT image reconstruction from gapped spectra, a sparse parameter estimation approach based on Sparse Iterative Covariance-based Estimation (SPICE) is proposed in this study. By utilizing a sparse parameter estimation framework to directly resolve depth-dependent components from discontinuous interferograms, SPICE enhances axial resolution while suppressing sidelobe artifacts inherent in standard interpolation. Experiments on multi-layered tape, oral epithelium, and finger skin show that SPICE visually suppresses gap-induced sidelobe artifacts and improves structural interpretability under representative gap conditions. Quantitative evaluations on multi-layer tape and biological tissues show that SPICE reduces axial FWHM by 30-45%, increases SSIM by 0.15-0.25, and achieves significantly lower computational cost than GAPES (p < 0.01).