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DOI 10.3390/children13060747

Медицинская библиотека · Children (Basel, Switzerland) · 2026

Life-Threatening Complications and Intensive Care of Diffuse Neonatal Hemangiomatosis of the Liver in a One-Month-Old Girl: A Case Report.

Tukhvatullina Regina R, Matinyan Nune V, Akimov Vasiliy A, Milutis Raisa V, Belysheva Tatiana S, Turkia Lana R, Chufistova Ekaterina V, Muftakhova Guzel M, Karmanova Julietta A, Kazantsev Anatoly P, Reshetnikova Vera V, Valiev Timur T, Kirgizov Kirill I, Gorbunova Tatiana V, Varfolomeeva Svetlana R, Shubina Irina Zh, Kiselevskiy Mikhail V

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Аннотация

Background

An infantile hemangioma (IH) is a benign lesion that develops as a result of pathologically dysregulated proliferation of the endothelial cells of the capillaries, typically appearing within the first three years of life. The disease is found mostly on the skin and-less often-in the internal organs. Although IH generally has a good prognosis and may sometimes undergo spontaneous regression, certain types of IH with a specific form, localization, and size may lead to life-threatening conditions including impairment of vital functions. This determines the need for precise diagnostics and treatment. Case presentation: The paper presents a clinical observation of an infant in the first months of life with IH presenting as diffuse hepatic hemangiomatosis and a hemangioma of the left eyebrow area. The IH was associated with life-threatening conditions. However, effective treatment with the non-selective β-adrenoblocker propranolol led to a positive outcome and the resolution of complications.

Conclusions

This case demonstrates the critical importance of timely diagnosis and treatment for lesions that, while benign, can lead to fatal complications if not addressed promptly.

Для цитирования: Tukhvatullina Regina R, Matinyan Nune V, Akimov Vasiliy A, Milutis Raisa V, Belysheva Tatiana S, Turkia Lana R, Chufistova Ekaterina V, Muftakhova Guzel M, Karmanova Julietta A, Kazantsev Anatoly P, Reshetnikova Vera V, Valiev Timur T, Kirgizov Kirill I, Gorbunova Tatiana V, Varfolomeeva Svetlana R, Shubina Irina Zh, Kiselevskiy Mikhail V. Life-Threatening Complications and Intensive Care of Diffuse Neonatal Hemangiomatosis of the Liver in a One-Month-Old Girl: A Case Report.. Children (Basel, Switzerland). 2026. DOI: 10.3390/children13060747.
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