Kyrle's disease : a cutaneous marker of renal disorder.

Twenty one cases of Kyrle's disease were subjected to a thorough clinical examination and various investigations in order to find out the association of Kyrle's disease with other systemic disorders and to elucidate the association between specific biochemical abnormalities and Kyrle's disease. It was found that all the cases of Kyrle's disease were associated with systemic disorders and that the major systemic disorder was nephropathy. The significant biochemical abnormality detected was a raised phosphorus level. So it is probable that the elevated phosphorus may be triggering the occurrence of Kyrle's disease.