Journal of oral rehabilitation · 2026
Efficacy of Local Treatment in Patients With Rheumatic Diseases Affecting the Temporomandibular Joint-A Systematic Review.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Ulmner Mattias, Stenwall Elizabeth, Mermer Selihattin, Lund Bodil
Аннотация
BACKGROUND: Temporomandibular joint (TMJ) involvement in rheumatic inflammatory arthropathies (RIA) has been sparsely described, and evidence regarding local treatment options for affected TMJs remains limited.
OBJECTIVES: To perform a systematic review (SR) regarding local treatments for TMJ involvement in RIA and evaluate their effects on pain management, disease improvement, quality of life, health economics, and adverse events.
METHODS: According to the PICO framework, patients with RIA were defined as the population, local TMJ treatment as the intervention, and alternative treatments, placebo, or no treatment as comparators. Outcome measures included maximum interincisal opening (MIO) and TMJ pain. A comprehensive search strategy was developed and applied to five databases.
RESULTS: The search generated 14 193 studies of which 33 met the inclusion criteria. All included studies had moderate or high risk of bias. Meta-analyses were conducted with due consideration of these limitations. Patients with juvenile idiopathic arthritis (JIA) or RIA (excluding JIA) having total joint replacement were analysed and JIA patients demonstrated better outcome both regarding MIO (p = 0.006, I2 = 86.8%) and TMJ pain (p = 0.02, I2 = 82.2%). No significant findings were observed in the remaining meta-analyses. A critical appraisal suggests that intra-articular corticosteroid injections might be beneficial for JIA patients.
CONCLUSION: The listed results have a low level of evidence and should be interpreted with caution. Nevertheless, this appears to be the only SR specifically evaluating local TMJ treatments in RIA. Ways of decreasing bias and increasing cohort sizes seem necessary for expanding knowledge.
OBJECTIVES: To perform a systematic review (SR) regarding local treatments for TMJ involvement in RIA and evaluate their effects on pain management, disease improvement, quality of life, health economics, and adverse events.
METHODS: According to the PICO framework, patients with RIA were defined as the population, local TMJ treatment as the intervention, and alternative treatments, placebo, or no treatment as comparators. Outcome measures included maximum interincisal opening (MIO) and TMJ pain. A comprehensive search strategy was developed and applied to five databases.
RESULTS: The search generated 14 193 studies of which 33 met the inclusion criteria. All included studies had moderate or high risk of bias. Meta-analyses were conducted with due consideration of these limitations. Patients with juvenile idiopathic arthritis (JIA) or RIA (excluding JIA) having total joint replacement were analysed and JIA patients demonstrated better outcome both regarding MIO (p = 0.006, I2 = 86.8%) and TMJ pain (p = 0.02, I2 = 82.2%). No significant findings were observed in the remaining meta-analyses. A critical appraisal suggests that intra-articular corticosteroid injections might be beneficial for JIA patients.
CONCLUSION: The listed results have a low level of evidence and should be interpreted with caution. Nevertheless, this appears to be the only SR specifically evaluating local TMJ treatments in RIA. Ways of decreasing bias and increasing cohort sizes seem necessary for expanding knowledge.