The American journal of gastroenterology · 2026
Greater Esophageal Cancer Burdens in Rural United States: A Surveillance, Epidemiology, and End Results Program Analysis.
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Gerber Annabel, Yoon Ji Yoon, Hur Chin, Rubenstein Joel H
Аннотация
AIM: To compare rural and urban trends in esophageal cancer (EC) incidence and mortality, including adenocarcinoma (EAC), squamous cell carcinoma (ESCC), and esophagogastric junction adenocarcinoma (EGJAC).
METHODS: Joinpoint analysis of Surveillance, Epidemiology, and End Results (SEER) registries from 1992 through 2022.
RESULTS: EAC incidence and mortality were greater in rural areas, with trends diverging around 1999. EGJAC incidence and mortality and ESCC incidence decreased in urban areas and had no significant trend in rural areas.
CONCLUSION: There are substantial disparities in EC incidence and mortality trends by rurality. Understanding the cause of these trends could support cancer control efforts.
METHODS: Joinpoint analysis of Surveillance, Epidemiology, and End Results (SEER) registries from 1992 through 2022.
RESULTS: EAC incidence and mortality were greater in rural areas, with trends diverging around 1999. EGJAC incidence and mortality and ESCC incidence decreased in urban areas and had no significant trend in rural areas.
CONCLUSION: There are substantial disparities in EC incidence and mortality trends by rurality. Understanding the cause of these trends could support cancer control efforts.