Timing of orchiopexy in children with congenital undescended testis in Latin America: A multicenter retrospective study.
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Oliveros-Rivero Jorge, Cabrera-Johnson Manuel, Gonzalez Sebastian Tobia, Rincon-Torres César Augusto, Yanowsky-Reyes Guillermo, González-Zamora José Francisco, Orjuela-Rodríguez Camilo Alberto, Bolaños-Gómez Andrea Patricia, Espinola-Gómez Carla Fabiola, Ormaechea-Fossati Martín Alvaro, Aranda-Alberto Mery Yanet, Fadil-Iturralde José Luis, Villalta-Vargas Marcelo, Moraes Isabela Picolotto-, Fernández-Alcaraz David Adrián, Fajardo-Ponce Gabriela, Garrido-Flores Matías, Alston Celeste, Castillo-Fernández Ana María, Enríquez-Morales Yadira Marilú, Almeida-Calado Adriano, Lanza-Gradiz Kriss Aileen, Tapia-Garibay Jorge Ignacio, Bastías-Campos Camila, Arboleda-Bustan Jenny Elizabeth, Marte-Aracena Eva Maria, Ovalle-Diaz Johanna, Ramírez-Rivera Jorge Isaac, Concha-Gutiérrez Carolina, Merchand-Herrera Giselle Mariana, Jiménez-Rivera Michelle
Аннотация
OBJECTIVE: To evaluate the timing of orchiopexy in children with CUDT in Latin America.
STUDY DESIGN: Multicenter retrospective observational study including patients younger than 18 years with CUDT who underwent orchiopexy between January 1, 2023, and December 31, 2025, across participating Latin American centers. In an exploratory secondary analysis, a hierarchical multivariable logistic regression model, accounting for clustering by participating hospital, was used to assess factors independently associated with orchiopexy after 18 months of age.
RESULTS: A total of 4481 patients from 14 countries and 31 centers were included. The median age at orchiopexy was 50 months (IQR 24-90), with a mean age of 60.5 months (95% CI 59.3-61.7). Only 18.2% of patients underwent surgery at or before 18 months of age, whereas 81.8% were treated after the recommended timeframe. The proportion treated by 18 months ranged from 4.7% in one participating hospital in Uruguay to 62.0% in one participating hospital in Argentina. Significant differences in age at surgery were observed across participating hospitals (p < 0.001). Among patients treated after 18 months, delayed referral and healthcare access barriers were the most frequently reported associated factors. In the hierarchical multivariable analysis accounting for clustering by participating hospital, intra-abdominal testicular location remained independently associated with lower odds of orchiopexy after 18 months of age (OR 0.71, 95% CI 0.55-0.91), whereas surgeon specialty, hospital level, and laterality were not independently associated with delayed orchiopexy.
CONCLUSIONS: More than 80% (more than four out of five) of children with CUDT treated at participating hospitals across Latin America underwent orchiopexy later than recommended by current international guidelines. These findings highlight an important gap in timely access to care and underscore the need for strategies that promote earlier diagnosis, prompt referral, and timely surgical treatment.