Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi · 2007
[Cellular parameters quantification, prognostic assessment of cervical squamous cell carcinoma].
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Pandeli R
Аннотация
UNLABELLED: Invasive squamous cell carcinoma develops from squamous intraepithelial lesions (SIL), that is why women with this tumour have the same epidemiologic characteristics to those with preinvasive precursor lesions.
MATERIAL AND METHODS: We have investigated 34 cases of intraepithelial squamous lesions, cytological and histopathological diagnosis.
RESULTS: For the biphasic quantification, there were taken in consideration all the established parameters (area, perimeter, diameter, long axis, short axis, roundness, eccentricity) and the results are presented for nucleus and nucleolus. For proliferative activity, there were quantified the mitotic activity index and mitotic density, the results being presented for high grade cervical intraepithelial neoplasia (CIN 3).
CONCLUSIONS: Biphasic measurement could be useful in diagnostic and prognostic of different grades of squamous carcinomas, adenocarcinomas or undifferentiated carcinomas, but not in assessment of malignancy risk of some dysplasias.
MATERIAL AND METHODS: We have investigated 34 cases of intraepithelial squamous lesions, cytological and histopathological diagnosis.
RESULTS: For the biphasic quantification, there were taken in consideration all the established parameters (area, perimeter, diameter, long axis, short axis, roundness, eccentricity) and the results are presented for nucleus and nucleolus. For proliferative activity, there were quantified the mitotic activity index and mitotic density, the results being presented for high grade cervical intraepithelial neoplasia (CIN 3).
CONCLUSIONS: Biphasic measurement could be useful in diagnostic and prognostic of different grades of squamous carcinomas, adenocarcinomas or undifferentiated carcinomas, but not in assessment of malignancy risk of some dysplasias.