The effect of chiropractic spinal manipulative therapy on salivary cortisol levels.

ObjectiveThis study examines the effect of chiropractic spinal manipulative therapy on salivary cortisol levels.DesignProspective case series over six weeks duration. The trial consisted of establishment of each individual's baseline cortisol level, a two week treatment period (4 treatments), and a two week post treatment period.SettingMacquarie University Chiropractic Research Centre.ParticipantsNine subjects (six male, three female), employed in a large corporation, volunteered to the trial of spinal manipulative therapy.Main outcome measuresSaliva samples were analysed using an Amerlex Radioimmunoassay Kit to determine the cortisol concentrations present.ResultsStatistical interpretation, after exclusion of an apparent outlying subject, revealed results of statistical significance (pConclusionThe initial evidence is inconclusive, however, the potential relationship demands further investigation. Additional research is necessary in measuring the physiological effects of Chiropractic spinal manipulative therapy. This method is currently being used in a larger randomised controlled trial.