Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2026
From Bruising to Blindness: A Practical Guide to Identifying and Managing Hyaluronic Acid Filler Complications.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Kamrani Payvand, Cox Sue Ellen, Beleznay Katie, Humphrey Shannon
Аннотация
PURPOSE: To provide a comprehensive, evidence-based review of the complications associated with hyaluronic acid (HA) dermal fillers and to offer practical guidance for their identification, prevention, and management.
DESIGN: Narrative review of the peer-reviewed literature, consensus guidelines, and postmarket surveillance data addressing the classification, pathophysiology, prevention, and treatment of HA filler complications.
FINDINGS: Hyaluronic acid fillers carry a favorable safety profile, with severe complications reported in fewer than 0.01% of injection sites. Complications are classified by onset. Early-onset events include ecchymosis, injection-site and hypersensitivity reactions, product displacement, and vascular occlusion. Late-onset events include biofilm-associated infection, delayed inflammatory nodules, granulomas, and hyperpigmentation. Vascular occlusion is the most feared complication and may progress to skin necrosis, vision loss, or stroke; prompt recognition and high-dose hyaluronidase, increasingly aided by ultrasound guidance, are central to management. Prevention rests on sound anatomic knowledge, appropriate product selection, and careful injection technique, while treatment is tailored to the specific complication.
SUMMARY: As filler use continues to expand, clinicians must be prepared to recognize, prevent, and manage the full spectrum of complications. This review consolidates current evidence into a practical framework intended to support safe practice and optimal patient outcomes.
DESIGN: Narrative review of the peer-reviewed literature, consensus guidelines, and postmarket surveillance data addressing the classification, pathophysiology, prevention, and treatment of HA filler complications.
FINDINGS: Hyaluronic acid fillers carry a favorable safety profile, with severe complications reported in fewer than 0.01% of injection sites. Complications are classified by onset. Early-onset events include ecchymosis, injection-site and hypersensitivity reactions, product displacement, and vascular occlusion. Late-onset events include biofilm-associated infection, delayed inflammatory nodules, granulomas, and hyperpigmentation. Vascular occlusion is the most feared complication and may progress to skin necrosis, vision loss, or stroke; prompt recognition and high-dose hyaluronidase, increasingly aided by ultrasound guidance, are central to management. Prevention rests on sound anatomic knowledge, appropriate product selection, and careful injection technique, while treatment is tailored to the specific complication.
SUMMARY: As filler use continues to expand, clinicians must be prepared to recognize, prevent, and manage the full spectrum of complications. This review consolidates current evidence into a practical framework intended to support safe practice and optimal patient outcomes.