[The submucosal structure of the endolymphatic sac of guinea pigs].

OBJECTIVE

To investigating the submucosal structure of the endolymphatic sac (ES), so as to analyse the role of ES in the function of inner ear.

METHOD: The temporal bone of the guinea pigs were cleared in methyl salicylate and inspected under a stereomicroscope. The ultrastructure of endolymphatic sac has been observed by transmission electron microscope.

RESULT: The extensive vascular system around the sac and has compact contact with sinus sigmoid. Its submucosal space comprises both arterioles and venules, as well as lymphatic sinus.

CONCLUSION

The result suggests that the ES is a very metabolically active structure and has a pressure regulating function. The disturbance of endolymphatic resorptive function seems to result endolymphatic hydrops after the vascular supply poverty of endolymphtic sac. It's may be the causative factor of Meniere's disease.