Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2025
Diagnostic Accuracy of Neuromuscular Ultrasound for Carpal Tunnel Syndrome: A Real-World Study.
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Roy Ujjawal, Cartwright Michael S, Srivastava Achal Kumar, Dixit Abhishek, Panwar Ajay, Vanchi Meenakshi, Ramamurthy Guhan, Shivaraman M M Arun, Ayan Saankritya, Verma Saket, Lal Prabhat Kumar
Аннотация
BACKGROUND AND PURPOSE: To determine the diagnostic accuracy of median nerve ultrasound in suspected cases of carpal tunnel syndrome (CTS) in a prospective, real-world study.
METHODS: This prospective study was carried out over one year at Roy Neuro Care Centre, Ranchi, Jharkhand, India. The clinical, electrophysiologic, and ultrasonographic findings in suspected cases of CTS were collected. A history and physical examination consistent with CTS were considered the gold standard for diagnosis.
RESULTS: A total of 134 patients with symptoms suggestive of CTS were enrolled, and both wrists were examined. The diagnostic accuracy of various ultrasound parameters including maximum cross-sectional area (CSA) of the median nerve in the tunnel, difference between CSA at the level of the pronator quadratus compared to the carpal tunnel, and wrist-to-forearm ratio were evaluated by individual, parallel, and serial testing strategies using optimal cut-off values determined by the Youden Index. Parallel testing provided the highest sensitivity, making it suitable for screening, whereas serial testing produced the highest overall accuracy.
CONCLUSION: Median nerve ultrasound is an accurate diagnostic tool for CTS in a real-world setting.
METHODS: This prospective study was carried out over one year at Roy Neuro Care Centre, Ranchi, Jharkhand, India. The clinical, electrophysiologic, and ultrasonographic findings in suspected cases of CTS were collected. A history and physical examination consistent with CTS were considered the gold standard for diagnosis.
RESULTS: A total of 134 patients with symptoms suggestive of CTS were enrolled, and both wrists were examined. The diagnostic accuracy of various ultrasound parameters including maximum cross-sectional area (CSA) of the median nerve in the tunnel, difference between CSA at the level of the pronator quadratus compared to the carpal tunnel, and wrist-to-forearm ratio were evaluated by individual, parallel, and serial testing strategies using optimal cut-off values determined by the Youden Index. Parallel testing provided the highest sensitivity, making it suitable for screening, whereas serial testing produced the highest overall accuracy.
CONCLUSION: Median nerve ultrasound is an accurate diagnostic tool for CTS in a real-world setting.