Abnormal uterine bleeding and underlying hemostatic disorders: report of a consensus process.

An ad hoc consensus group determined that the prevalence of von Willebrand's disease in females with heavy menstrual bleeding is approximately 13%, but the severity of the disorder varies and, consequently, the overall clinical impact remains unknown. Consensus recommendations are presented, which include [1] a structured history for screening females with heavy menstrual bleeding; [2] a collaborative, multidisciplinary evaluation, and [3] a strategy for future basic science and clinical investigation.