A Twist in the Tale: Rare Diagnosis of Lipomatosis of the Appendix.

A 66-year-old white male with a history of diverticulosis and prediabetes presented with right lower quadrant (RLQ) abdominal pain lasting 1 month. On physical examination, the abdomen was soft without tenderness or palpable masses. CT imaging showed an enlarged appendix with a diameter of 1 cm with no surrounding inflammation. A laparoscopic appendectomy was performed, and the patient's symptoms resolved within 3 weeks. Histopathology revealed lipomatosis of the appendix, an extraordinarily rare diagnosis which has only been reported five times prior to our case. This case study aims to increase available information on this disease to aid future diagnosis and treatment.