Conduction System Versus Right Ventricular Pacing in Patients Undergoing TAVR: A Multicenter Propensity-Matched Study.
Обработка статьи · этапы, ошибки и управление
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Diez-Delhoyo Felipe, Sanz-Sanchez Jorge, Muntane-Carol Guillem, Amat-Santos Ignacio Jesus, Oteo Dominguez Juan Francisco, Rivera-Lopez Ricardo, Asmarats Lluis, Pan Manuel, Novoa Medina Jose Maria, Franco-Pelaez Juan Antonio, Cuellas Carlos, Roa-Garrido Jessica, Tamargo Maria, Veiga Gabriela, Herrero-Brocal Marta, Valentin Garcia Pablo Miguel, Garcia-Lara Juan, Cuesta Javier, Valencia-Serrano Felix, Pimienta-Gonzalez Raquel, Linares Vicente Jose Antonio, Palazuelos-Molinero Jorge, Gomez-Blazquez Ivan, Navarro-Manchon Josep, Di Marco Andrea, Garnacho-Gomez Luis, Vela-Martin Paula, Martin-Arriscado Cristina, Cebada Fernando Sarnago
Аннотация
OBJECTIVES: This study sought to compare long-term clinical outcomes of CPP vs RVP in patients requiring permanent pacing after TAVR.
METHODS: Registro de Estimulación Fisiológica-TAVR is a retrospective, multicenter nationwide registry including patients undergoing TAVR and pacemaker implantation within 30 days. Propensity score matching (1:1) was performed using baseline clinical and echocardiographic variables, yielding 466 matched pairs. The primary endpoint was the composite of cardiovascular death or HF hospitalization. Cox proportional hazards models were used for time-to-event analyses. Median follow-up was 24 months.
RESULTS: In the propensity score-matched cohort, CPP was associated with a lower incidence of the primary endpoint than RVP (9.7% vs 17.6%; HR: 0.57; 95% CI: 0.39-0.83; P = 0.003). This difference was driven by fewer HF hospitalizations (7.9% vs 13.9%; HR: 0.57; 95% CI: 0.37-0.86; P = 0.008). No significant differences were observed in cardiovascular death or all-cause mortality between groups.
CONCLUSIONS: In this multicenter propensity score-matched study, CPP after TAVR was associated with a lower risk of the primary endpoint, driven by fewer HF hospitalizations. These findings support the need for further randomized clinical trials to evaluate the role of CPP in post-TAVR patients requiring ventricular pacing.