European journal of applied physiology · 2026
Sex- and condition-dependent muscle oxygenation, performance fatigability, and post-occlusive reactive hyperemic responses to blood flow restriction exercise.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Kwak Minyoung, Benitez Brian, Mitchinson Clara J, Snell Erik R, Kuhn Alaina N, Samaan Michael A, Butterfield Timothy, Samson Ashley, Pabian Patrick, Bergstrom Haley C
Аннотация
PURPOSE: This study examined sex- and condition-dependent differences in muscle oxygenation, performance fatigability (PF), and post-occlusive reactive hyperemic responses during moderate-pressure (40% of arterial occlusion pressure) blood flow restriction exercise (BFR), free-flow exercise (NON-BFR), and BFR without exercise (PASSIVE BFR).
METHODS: Fifteen males and fourteen females completed all three conditions in a randomized crossover design. Exercise consisted of unilateral, dynamic leg extensions performed at 30% of maximal voluntary isometric contraction (MVIC) using a 30-15-15-15 repetition protocol with 60-s inter-set recovery periods. During intervention and recovery sets, muscle oxygenation (SmO2) and deoxygenated hemoglobin (HHb) were assessed using near-infrared spectroscopy (NIRS). Pre- and post-intervention MVIC torque, and vascular occlusion test (VOT)-derived post-occlusive reperfusion slope (Slope 2) were evaluated. Linear mixed-effects models were used, with significance set at p < 0.05.
RESULTS: Compared with NON-BFR and PASSIVE BFR, BFR elicited lower SmO2 and greater HHb during the intervention, lower reoxygenation during recovery, and larger reductions in MVIC. Slope 2 increased following the interventions when collapsed across conditions (p = 0.032), with no condition effect detected. Males exhibited lower SmO2, greater HHb responses, and larger reductions in MVIC during BFR and NON-BFR compared with females. When collapsed across conditions, males demonstrated greater Slope 2 than females (p = 0.003).
CONCLUSION: Although BFR induced marked intramuscular deoxygenation and greater fatigability in both sexes, we did not detect a corresponding enhancement in post-exercise reactive hyperemic response, a finding that should be interpreted cautiously given the limited reliability of Slope 2.
METHODS: Fifteen males and fourteen females completed all three conditions in a randomized crossover design. Exercise consisted of unilateral, dynamic leg extensions performed at 30% of maximal voluntary isometric contraction (MVIC) using a 30-15-15-15 repetition protocol with 60-s inter-set recovery periods. During intervention and recovery sets, muscle oxygenation (SmO2) and deoxygenated hemoglobin (HHb) were assessed using near-infrared spectroscopy (NIRS). Pre- and post-intervention MVIC torque, and vascular occlusion test (VOT)-derived post-occlusive reperfusion slope (Slope 2) were evaluated. Linear mixed-effects models were used, with significance set at p < 0.05.
RESULTS: Compared with NON-BFR and PASSIVE BFR, BFR elicited lower SmO2 and greater HHb during the intervention, lower reoxygenation during recovery, and larger reductions in MVIC. Slope 2 increased following the interventions when collapsed across conditions (p = 0.032), with no condition effect detected. Males exhibited lower SmO2, greater HHb responses, and larger reductions in MVIC during BFR and NON-BFR compared with females. When collapsed across conditions, males demonstrated greater Slope 2 than females (p = 0.003).
CONCLUSION: Although BFR induced marked intramuscular deoxygenation and greater fatigability in both sexes, we did not detect a corresponding enhancement in post-exercise reactive hyperemic response, a finding that should be interpreted cautiously given the limited reliability of Slope 2.