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DOI 10.1016/j.farma.2026.08.006

Медицинская библиотека · Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria · 2026

[Translated article] Depression, stress and medication adherence in patients with type 2 diabetes: A crosssectional study in Mexico.

Portillo-Robledo Fátima Del Carmen, León-Mazón Marco Antonio, Ávila-Jiménez Laura, Díaz de León-Castañeda Christian, Toledano-Jaimes Cairo David

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Аннотация

OBJECTIVE

To describe the level of adherence to pharmacological treatment and explore, using a bivariate analysis, its unadjusted association with mental health variables (depression and stress) in patients with type 2.

METHOD: A cross-sectional study was conducted with 326 patients with T2D and beneficiaries of a multidisciplinary center of a social security institution in Morelos, Mexico. Sociodemographic, clinical, and mental health variables such as stress and depression were evaluated, in addition to adherence to pharmacological treatment in patients with T2D, using instruments with evidence of validity and reliability. Bivariate statistical analysis was used to evaluate the association between the variables of interest and pharmacological adherence.

RESULTS

A statistically significant association was found between pharmacological adherence with depression (χ2 = 7.3, p = 0.01; OR = 0.28, p = 0.01), and with depression and stress as concomitance (OR = 0.18, p = 0.02). No statistically significant associations were found with sociodemographic factors.

CONCLUSIONS

In this cross-sectional study, a bivariate association was observed between depression-and its co-occurrence with stress-and pharmacological adherence. These findings should be interpreted with caution and require confirmation through studies with adjusted analyses.

Для цитирования: Portillo-Robledo Fátima Del Carmen, León-Mazón Marco Antonio, Ávila-Jiménez Laura, Díaz de León-Castañeda Christian, Toledano-Jaimes Cairo David. [Translated article] Depression, stress and medication adherence in patients with type 2 diabetes: A crosssectional study in Mexico.. Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria. 2026. DOI: 10.1016/j.farma.2026.08.006.
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