Nursing open · 2026
Association Between Cdyn-Guided PEEP and Nursing Activities During PACU Recovery in Infants Undergoing One-Lung Ventilation: A Retrospective Observational Cohort Study.
СтатьяНаблюдательное исследованиеНазвание и аннотация: Перевод пока не подготовлен
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Hao Mingran, Zhang Bin, Han Yuejiao, Zhao Changbin, Dong Zhaoyuan, Song Benqin
Аннотация
AIM: To evaluate the association between Cdyn-guided PEEP during one-lung ventilation (OLV) and nursing activities in the post-anaesthesia care unit (PACU) among infants undergoing thoracoscopic surgery under general anaesthesia: DESIGN: Retrospective observational cohort study.
METHODS: A retrospective analysis was conducted on clinical data from infants with congenital pulmonary airway malformation (CPAM) who underwent thoracoscopic lobectomy at a Children's Hospital Affiliated to Shandong University between January 2022 and February 2025. Patients were classified according to the recorded intraoperative PEEP strategy actually delivered during OLV: Group P was managed with Cdyn-guided individualized PEEP; Group C was managed with fixed PEEP of 5 cmH2O. The primary outcome was PACU Nursing Activities Score (NAS). Baseline clinical characteristics, postoperative outcomes (incidence of delirium, pain scores), PACU observation time, and adverse events were compared between the two groups.
RESULTS: A total of 93 patients were included. Baseline characteristics were generally balanced, with most standardized mean differences < 0.2. After adjustment for prespecified covariates, Cdyn-guided PEEP was associated with a lower NAS score (adjusted mean difference = -3.75; 95% CI: -6.44 to -1.07; p = 0.007). Compared with Group C, Group P was also associated with a shorter PACU stay and a lower composite adverse event rate.
PATIENT OR PUBLIC CONTRIBUTION: No Patient or Public Contribution.
METHODS: A retrospective analysis was conducted on clinical data from infants with congenital pulmonary airway malformation (CPAM) who underwent thoracoscopic lobectomy at a Children's Hospital Affiliated to Shandong University between January 2022 and February 2025. Patients were classified according to the recorded intraoperative PEEP strategy actually delivered during OLV: Group P was managed with Cdyn-guided individualized PEEP; Group C was managed with fixed PEEP of 5 cmH2O. The primary outcome was PACU Nursing Activities Score (NAS). Baseline clinical characteristics, postoperative outcomes (incidence of delirium, pain scores), PACU observation time, and adverse events were compared between the two groups.
RESULTS: A total of 93 patients were included. Baseline characteristics were generally balanced, with most standardized mean differences < 0.2. After adjustment for prespecified covariates, Cdyn-guided PEEP was associated with a lower NAS score (adjusted mean difference = -3.75; 95% CI: -6.44 to -1.07; p = 0.007). Compared with Group C, Group P was also associated with a shorter PACU stay and a lower composite adverse event rate.
PATIENT OR PUBLIC CONTRIBUTION: No Patient or Public Contribution.