Medicine and science in sports and exercise · 2026
Quadriceps Strength Recovery Trajectories Associate with Pre-Operative Predictors but not Clinical Outcomes Following ACL Reconstruction.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
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Franek Madison, Arbeeva Liubov, Lee Hyunwook, Lartey Richard, Wang Xinxin, Hakan Ok Ahmet, Spang Jeffrey T, Ingersoll Christopher D, Hart Joe M, Büttner Christin, Favoreto Natalia, Creighton Robert A, Kamath Ganesh M, Lisee Caroline, Blackburn J Troy, Yang Mingrui, Li Xiaojuan, Pietrosimone Brian
Аннотация
PURPOSE: Quadriceps weakness following anterior cruciate ligament reconstruction (ACLR) is common, however distinct longitudinal strength trajectories not have been examined. This study aimed to i) identify strength trajectories measured pre-operatively to 12 months post-ACLR, and determine associations with ii) pre-operative demographics, patient-reported outcomes (PROs: Knee Injury and Osteoarthritis Outcome Score [KOOS], Tegner, Marx) and ACLR concomitant surgeries, and iii) clinical outcomes post-ACLR including cartilage compositional changes (via magnetic resonance imaging [MRI] T1ρ relaxation times) and 12-month KOOS.
METHODS: Isometric quadriceps strength was measured bilaterally pre-operatively and at 4, 6, and 12 months. Group trajectory modeling characterized longitudinal strength recovery in ACLR and uninvolved limbs, which were combined to define dual-limb recovery patterns. Tibiofemoral and patellofemoral cartilage composition was measured pre-operatively and at 12 months post-ACLR. Dirichlet regressions examined associations between trajectories and demographics, surgeries, PROs, and cartilage changes.
RESULTS: 59 participants were included (58% female; age, 21.9 ± 4.7y; BMI, 24.55 ± 3.7kg/m 2). Three combined trajectories were identified: bilaterally weak (51%), which demonstrated uninvolved limb strength declines and failure to recover ACLR limb pre-operative strength; bilaterally strong (38%), which demonstrated minimal uninvolved limb declines and ACLR limb pre-operative strength recovery; and weak uninvolved, strong ACLR limb (12%). Lower pre-injury Tegner scores associated with bilaterally weak membership (p = 0.01), where probability increased from 0.27 (score of 10) to 0.61 (score of 0). Medial meniscectomy associated most with bilaterally weak membership (p<.001, 0.86 probability). No associations were found between trajectories and clinical outcomes.
CONCLUSIONS: While individuals who failed to restore ACLR limb strength demonstrated bilateral quadriceps weakness pre-operatively, persons who demonstrated greater pre-operative bilateral strength recovered ACLR limb strength. Medial meniscectomy associated with an inability to restore quadriceps strength.
METHODS: Isometric quadriceps strength was measured bilaterally pre-operatively and at 4, 6, and 12 months. Group trajectory modeling characterized longitudinal strength recovery in ACLR and uninvolved limbs, which were combined to define dual-limb recovery patterns. Tibiofemoral and patellofemoral cartilage composition was measured pre-operatively and at 12 months post-ACLR. Dirichlet regressions examined associations between trajectories and demographics, surgeries, PROs, and cartilage changes.
RESULTS: 59 participants were included (58% female; age, 21.9 ± 4.7y; BMI, 24.55 ± 3.7kg/m 2). Three combined trajectories were identified: bilaterally weak (51%), which demonstrated uninvolved limb strength declines and failure to recover ACLR limb pre-operative strength; bilaterally strong (38%), which demonstrated minimal uninvolved limb declines and ACLR limb pre-operative strength recovery; and weak uninvolved, strong ACLR limb (12%). Lower pre-injury Tegner scores associated with bilaterally weak membership (p = 0.01), where probability increased from 0.27 (score of 10) to 0.61 (score of 0). Medial meniscectomy associated most with bilaterally weak membership (p<.001, 0.86 probability). No associations were found between trajectories and clinical outcomes.
CONCLUSIONS: While individuals who failed to restore ACLR limb strength demonstrated bilateral quadriceps weakness pre-operatively, persons who demonstrated greater pre-operative bilateral strength recovered ACLR limb strength. Medial meniscectomy associated with an inability to restore quadriceps strength.