Journal of clinical anesthesia · 2026
Difficulty climbing stairs or walking one block on the FRAIL scale is associated with adverse postoperative outcomes in older surgical patients.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Tan Tony, Yan Ellene, Alhamdah Yasmin, Nabipoor Majid, Butris Nina, Kapoor Paras, Saripella Aparna, Islam Sazzadul, Wong Jean, Chung Frances
Аннотация
BACKGROUND: Frail individuals represent a high-risk group for postoperative complications. The FRAIL (Fatigue, Resistance, Ambulation, Illnesses, and Weight Loss) scale is a self-reported tool for assessing frailty. While prior studies have linked overall FRAIL scores with adverse outcomes, the association of individual questions with postoperative complications has never been extensively studied.
METHODS: This post-hoc analysis included 677 surgical participants aged ≥65 years from the Postoperative Functional Disability in Unrecognized Cognitive Impairment (POF) and Detection of Cognitive Impairment (Detect-CI) studies. Preoperative frailty was assessed using the 5-item FRAIL scale. Multiplicity-adjusted multivariable logistic and linear regression models were used to examine associations between frailty status and individual FRAIL questions with postoperative outcomes.
RESULTS: Among the five individual FRAIL questions, inability to climb one flight of stairs (Q2: resistance) was most associated with postoperative outcomes. Participants reporting difficulty with resistance had higher odds of 30-day non-home discharge (OR: 2.47, 95% CI: 1.43, 4.33), composite adverse outcomes (OR: 1.68, 95% CI: 1.14, 2.49), and 22% longer hospital stay (β: 0.20, 95% CI: 0.08, 0.32). The individual question on inability to walk one block (Q3: ambulation) was also associated with higher odds of 30-day non-home discharge (OR: 2.93, 95% CI: 1.67, 5.31) and 19% longer hospital stay (β: 0.18, 95% CI: 0.06, 0.29).
CONCLUSIONS: Of the five FRAIL scale questions, difficulty climbing one flight of stairs (resistance) was most associated with 30-day postoperative outcomes, followed by difficulty walking one block (ambulation). In busy preoperative clinics, these two yes/no questions may offer a quick and practical screening approach for identifying high-risk patients and those in need of prehabilitation.
METHODS: This post-hoc analysis included 677 surgical participants aged ≥65 years from the Postoperative Functional Disability in Unrecognized Cognitive Impairment (POF) and Detection of Cognitive Impairment (Detect-CI) studies. Preoperative frailty was assessed using the 5-item FRAIL scale. Multiplicity-adjusted multivariable logistic and linear regression models were used to examine associations between frailty status and individual FRAIL questions with postoperative outcomes.
RESULTS: Among the five individual FRAIL questions, inability to climb one flight of stairs (Q2: resistance) was most associated with postoperative outcomes. Participants reporting difficulty with resistance had higher odds of 30-day non-home discharge (OR: 2.47, 95% CI: 1.43, 4.33), composite adverse outcomes (OR: 1.68, 95% CI: 1.14, 2.49), and 22% longer hospital stay (β: 0.20, 95% CI: 0.08, 0.32). The individual question on inability to walk one block (Q3: ambulation) was also associated with higher odds of 30-day non-home discharge (OR: 2.93, 95% CI: 1.67, 5.31) and 19% longer hospital stay (β: 0.18, 95% CI: 0.06, 0.29).
CONCLUSIONS: Of the five FRAIL scale questions, difficulty climbing one flight of stairs (resistance) was most associated with 30-day postoperative outcomes, followed by difficulty walking one block (ambulation). In busy preoperative clinics, these two yes/no questions may offer a quick and practical screening approach for identifying high-risk patients and those in need of prehabilitation.