Atencion primaria · 2026
[Appropriateness of strong opioid prescribing chronic non-cancer pain in primary care: a cross-sectional study].
Аннотация на английскомСтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Díaz-Piñeiro Jorge, González-González José Ignacio, Infante-Peralta Eric Bismar, Solís-González Miguel, Solís-González Luis, Palomar-Ramos Guillermo
Аннотация
OBJECTIVE: To assess the appropriateness of strong opioid prescribing for chronic non-cancer pain (CNCP) in primary care and to analyse factors associated with inappropriate prescribing.
DESIGN: Cross-sectional observational study. SITE: Three primary care centres in a health area in northern Spain.
PARTICIPANTS: Active prescriptions of strong opioids in adult patients with CNCP. A total of 441 prescriptions corresponding to 387 patients were analysed.
INTERVENTIONS: No interventions were performed. A retrospective review of prescriptions and electronic health records was conducted.
MAIN MEASUREMENTS: Therapeutic appropriateness according to eight clinical recommendations on indication, previous analgesic escalation, concomitant treatment and safety. Descriptive analysis and multivariable logistic regression were performed.
RESULTS: Mean age was 67.1years (SD: 16.0), and 71.4% of prescriptions corresponded to women. Overall, 82.8% of prescriptions were considered inappropriate. The most frequent non-adherence criterion was concomitant benzodiazepine use (55.1%). In the multivariable model, age (OR: 1.02; 95%CI: 1.00-1.04; P=.038) and concomitant antidepressant treatment (OR: 4.76; 95%CI: 2.17-10.64; P<.001) were associated with inappropriate prescribing. A high-risk clinical profile was observed in 31.5% of prescriptions.
CONCLUSIONS: Strong opioid prescribing for CNCP showed a high proportion of inappropriate use. These findings support the implementation of prescribing review and medication safety interventions in primary care.
DESIGN: Cross-sectional observational study. SITE: Three primary care centres in a health area in northern Spain.
PARTICIPANTS: Active prescriptions of strong opioids in adult patients with CNCP. A total of 441 prescriptions corresponding to 387 patients were analysed.
INTERVENTIONS: No interventions were performed. A retrospective review of prescriptions and electronic health records was conducted.
MAIN MEASUREMENTS: Therapeutic appropriateness according to eight clinical recommendations on indication, previous analgesic escalation, concomitant treatment and safety. Descriptive analysis and multivariable logistic regression were performed.
RESULTS: Mean age was 67.1years (SD: 16.0), and 71.4% of prescriptions corresponded to women. Overall, 82.8% of prescriptions were considered inappropriate. The most frequent non-adherence criterion was concomitant benzodiazepine use (55.1%). In the multivariable model, age (OR: 1.02; 95%CI: 1.00-1.04; P=.038) and concomitant antidepressant treatment (OR: 4.76; 95%CI: 2.17-10.64; P<.001) were associated with inappropriate prescribing. A high-risk clinical profile was observed in 31.5% of prescriptions.
CONCLUSIONS: Strong opioid prescribing for CNCP showed a high proportion of inappropriate use. These findings support the implementation of prescribing review and medication safety interventions in primary care.