Cancer investigation · 2026
The Evolving Role of Surgery in Hepatocellular Carcinoma Management: From Resection to Multidisciplinary Strategy.
СтатьяОбзорНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
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История · было → стало
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Okabayashi Takehiro, Tabuchi Motoyasu, Tokumaru Teppei, Uemura Sunao, Tamura Shuta
Аннотация
BACKGROUND: Hepatocellular carcinoma (HCC) frequently develops in the setting of chronic liver disease, making its management uniquely complex and historically centered on surgery.
RECENT FINDINGS: Advances in locoregional therapies, molecular targeted agents, and immune checkpoint inhibitors have profoundly transformed treatment algorithms. Immunotherapy-based combinations achieve deep and durable responses, enabling downstaging, conversion surgery, and perioperative strategies previously considered unfeasible.
CONCLUSION: In the contemporary era, surgeons serve not only as technical operators but as strategic leaders within multidisciplinary teams, integrating evolving systemic and local therapies to achieve durable oncologic outcomes.
RECENT FINDINGS: Advances in locoregional therapies, molecular targeted agents, and immune checkpoint inhibitors have profoundly transformed treatment algorithms. Immunotherapy-based combinations achieve deep and durable responses, enabling downstaging, conversion surgery, and perioperative strategies previously considered unfeasible.
CONCLUSION: In the contemporary era, surgeons serve not only as technical operators but as strategic leaders within multidisciplinary teams, integrating evolving systemic and local therapies to achieve durable oncologic outcomes.